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10.1073/pnas.2221116120 [DOI] [PMC free article] [PubMed] [Google Scholar] Pencik J., Philippe C., Schlederer M., Atas E., Pecoraro M., Grund-Grschke S., et al

However, in clinical applications, targeted therapies often exhibit multi-target effects, which can lead to both toxic side effects on normal cells and enhanced tumor cell cytotoxicity [37]