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41589_2021_915_MOESM13_ESM.mpeg Supplementary Video 11 Representative movie for 100 ns MD simulation of GPX4 K48A with the camera zoomed in for a close-up of the active site

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Four studies found no significant difference in serum or plasma serine levels between children and adults with or without autistic disorder, PDD-NOS, Asperger's Syndrome or autism spectrum disorders (mixed sample) [60, 69, 70, 75], one study showed a trend towards a decrease in children with autistic disorder [60] and another reported significantly increased plasma serine in children with autism spectrum disorders [87] and significantly lower levels of serine were reported for platelet poor plasma in autism spectrum disorders [86]

IV-mediated ROS on cellular components These IV-mediated functions, such as the effects on TLR family members, inflammation, matrix metalloproteinases (MMPs), and ER stress, in host cells are triggered, at least in part, by the regulation of Nrf2/ROS signaling and the signaling pathways of PI3K/AKT, p38/JNK MAPK, and NF-kB

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