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For patients aged 50 years and older, recommended screening should include age-appropriate investigations in accordance with prevailing clinical practice guidelinessuch as colonoscopy for colorectal cancer, mammography for breast cancer, and cervical cytology or HPV testing as indicated

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The relevance here is evidential, not procedural: because delivery and stability vary so much, comparing results across products and studies is genuinely difficult, and that heterogeneity is one reason a clean answer to the title question has been so slow to emerge