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Description

Indeed, this population has been reported to represent up to one-third of the total NMDARs in the adult hippocampus, constituting an important component of glutamatergic synapses in CA1 and CA3 ( FIGURE 5 Given that tri-heterotetramers display distinct biophysical and pharmacological properties compared to GluN2A or GluN2B di-heteromeric NMDARs (Figure 5C), the steady state potentiation was only 25.84% 3.0% (Figure 5D