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Mitochondrial biogenesis-associated proteins, particularly Nrf-1/2, act as transcription factors enhancing the expression of mitochondrial antioxidant genes (including manganese superoxide dismutase, catalase, peroxiredoxins 3 and 5, uncoupling protein 2, thioredoxin 2, and thioredoxin reductase), highlighting the antioxidant properties of mitochondrial biogenesis [94]

4 Conclusion Since the concept of tumor vaccines was proposed, researchers have never ceased to develop and evolve the performance of tumor vaccines, although their clinical efficacies have been limited

However, this question is controversial in humans [19-21]

Nano lipid carriers as a promising drug delivery carrier for neurodegenerative disorders - an overview of recent advances

Furthermore, search strategy analysis demonstrated that spatially precise search is promoted by adult neurogenesis and the involvement of the ventral hippocampus in coarse spatial goal-orientated search and cue-dependent navigation 57,58