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Even though vitamin B12 is water soluble, tissue half-life (how long it stays in the body) averages 13 days in healthy cats and is reduced to approximately 5 days in cats with gastrointestinal diseases or poor overall health

This imbalance (an increased Th17/Treg ratio) is a typical feature of autoimmune and chronic inflammatory diseases, disrupting immune homeostasis and promoting inflammation in ovarian and metabolic tissues

(ii) trigger fidelity in vivo

In both species, the foundress produces an initial haploid male egg followed by a series of female eggs and all offspring grow rapidly during a protonymph and deutonymph stage on the same host

Cell 113(7):935944