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Linus Pauling Institute Oregon State University Updated in September 2002 by: Jane Higdon, Ph.D

In the setting of diet-induced hyperinsulinaemia and obesity, insulin dose-dependently increases the formation of acinar to ductal metaplasia via trypsin and the insulin receptor (InsR) [252]

In cancer cells, glutamine is transported into cell through the amino acid transporter ASCT2/SLC1A5

Martignoni M, Groothuis GMM, de Kanter R (2006) Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction

Additionally, inconsistent findings across studies are due to heterogeneity in sequencing platforms, CST classification methods and analytical pipelines