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Without adequate taurine, the mitochondria fail to build these subunits correctly, creating an "electron bottleneck." When electrons back up in the chain, they inappropriately bind with oxygen to generate massive amounts of destructive superoxide radicals, sparking severe intracellular oxidative stress

Xiao et al., 2019)

Biomarker Assessment: Who May Benefit Most from Glutathione Support Individuals with documented oxidative stress markerssuch as elevated malondialdehyde (MDA), reduced superoxide dismutase (SOD), or low plasma glutathionemay represent candidates for glutathione supplementation

Additionally, they found that mitochondrial dynamics abnormalities were present in the early stages of AD development