hydrogen peroxide glutathione peroxidase Figure 3 from Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities Chemistry of Hydrogen Peroxide Formation

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Brain Research 909(12):187193 Henn A, Lund S, Hedtjarn M, Schrattenholz A, Porzgen P, Leist M (2009) The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

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Notably, genes involved in the TSS pathway, cystine uptake and glutathione recycling (such as CBS, CSE, SLC7A11 and GSR) were DNA hypomethylated after DMF treatment 30 , supporting a regulatory effect of DMF on these pathways