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Treatment of B6 mice with the GLS1 inhibitor BPTES significantly reduced histological scores in the spinal cord of affected animals, lowered the number of CD4 + T cells, IL-17A and IFN-producing CD4 + T cells in the spinal cord, substantially decreased clinical scores and weight loss, and ameliorated experimental autoimmune encephalomyelitis (47)

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Eryptosis and inherited blood disorders Eryptosis is observed in conditions like sickle cell anemia [80], thalassemia, glucose-6-phosphate dehydrogenase deficiency [412], among other hemolytic diseases

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Studies have also investigated its potential applications for Alzheimers disease and other neurodegenerative conditions