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All full-length Ab DPcob forms are more active than the isolated DGC domain, indicating that the presence of the photocobilin domain plays a role in maintaining the DGC activity

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Strbe et al., 2021), the and combined score (08) = the sum of the analyzed affected areas (04) and karyopyknotic cells in the brain areas (04), as follows

Bonnan et al., 2021) further arguing against inadequate CNS penetration and trapped inflammation as the primary driver of progression

N high = total number of DDI, at high-risk across all databases