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Oral absorption is considered too undependable to rely on in patients with pernicious anemia or other conditions resulting in malabsorption of vitamin B 12

This includes Celiac disease, Cystic Fibrosis, Crohns disease and any intestinal issue that degrades the intestinal lining

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Manuel Serrano, a researcher at the Institute for Research in Biomedicine in Spain during the time of the study who has recently moved to Altos Labs in the United Kingdom and co-lead author of this study, they decided to study the impact of vitamin B12 on cellular reprogramming and tissue regeneration after an unexpected finding when they analyzed how the microbial populations of the colon change during reprogramming