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Reduced CYP3A5 activity has been observed in Caucasian children, who are at greater risk to develop vincristine-induced side effects (Dennison et al., 2006

Interaction of bilirubin and biliverdin with reactive nitrogen species

10.1111/j.1365-2958.2010.07418.x 133 JesaitisA

DON, deoxynivalenol

Among the 25% of GBMs exhibiting ser/gly pathway hyperactivation, ~13% of cases harbor genetic amplifications and mutations in PSPH, underscoring the significance of PSPH and de novo ser/gly synthesis pathway in the pathogenesis of GBM [21]