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Pak et al., 2018), especially superoxide, which is rapidly converted by superoxide dismutase 2 (SOD2) to hydrogen peroxide

Abstract Glutathione S-transferases (GSTs) constitute an important multifunctional enzyme family that plays vital roles in cellular detoxification and protecting organisms against oxidative stress caused by reactive oxygen species (ROS)

The strongest counter is methodological

To determine if GSH precursors accumulate and are possibly rerouted upon halting GSH synthesis in vivo, we performed targeted metabolite analysis on tissues from Gclc WT and KO mice

Loss of astrocytic glutamate transporters in Wernicke encephalopathy