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In addition, it will be interesting to distinguish between UPS-dependent and UPS-independent anticancer activities of copper complexes

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CAR-T cells have a particular effect in treating solid tumors such as renal cell carcinoma, HER2 positive sarcoma, ovarian cancer (94), and colorectal cancer (95)

Development of Small-Molecule Probes That Selectively Kill Cells Induced to Express Mutant Ras

Western blotting Cells were lysed in RIPA buffer (201mM Tris-HCl (pH 7.5), 1501mM NaCl, 11mM EDTA, 11mM EGTA, 1% NP-40, 0.5% sodium deoxycholate, and 0.1% SDS), supplemented with protease and phosphatase inhibitor cocktails (1% v/v each)