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Also levels of cleaved PARP (PolyADP ribose polymerase) 42 were detected with the appearance of a 90 kDa lower band as opposed to 113 kDa uncleaved PARP in GNE knockdown cells indicative of DNA damage (Fig

Gene expression values for genes common with differentially expressed genes and different gene signatures (see gene lists section) were plotted as heatmaps using the cluster map function in the seaborn package after conversion of read counts to transcripts per million (TPM), followed by z-scoring across the experimental conditions to avoid biases due to absolute values of gene expression

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Not suitable for children, pregnant women or breastfeeding women

Among the most commonly reported complications are fibrosis of the cervix, vagina, and surrounding connective tissue, leading to decreased elasticity, vaginal shortening, and stenosis [109,110,111]