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Intermittent hypoxia preconditioning alleviates chronic hypoxia-induced cognitive impairment in mice by inhibiting -syn phosphorylation and aggregation The above study found that chronic persistent hypoxia-induced irreversible cognitive impairment in mice

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The S 1 PESs for each antimetabolite contain two energy minima, one being the metal-to-ligand charge transfer (MLCT) and another the ligand- eld (LF) state