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doi: 10.1007/s11064-005-8826-8

It is commonly used as part of hormone replacement therapy (HRT) for individuals looking to support healthy aging, improve muscle mass, and enhance overall well-being

This decline correlates with decreased healing capacity and reduced tissue regeneration throughout the body

In DKD, in response to severe or persistent inflammation, TECs undergo EMT through various signaling pathways, such as TGF-, Wnt/-catenin, PI3K/Akt, JAK/STAT, and Notch pathways (7175)