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It seems that chemotherapy regimens (drug or combination of drugs administered and dosing), methods of pain assessment and the individual patient characteristics (presence of comorbidities associated with increased risk of neuropathy, such as diabetes, depression, insomnia or genetic particularities) are some of the several factors that may influence on the onset of CIPN and the severity of symptoms

The Pathogenesis of Chronic Obstructive Pulmonary Disease: Advances in the Past 100 Years

For example, each cell in the electroplax of Torpedo californica (pictured here) can produce 0.15 volts (V), or about 1/10 of the voltage generated by a AA battery

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or iii) high risk of bias (plausible bias that seriously weakens confidence in the results) if a high risk of bias was present in one or more domains