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Targeting the TGF-/Smad3 signaling pathway significantly attenuates renal fibrosis (Yasuda et al., 2021)

Nature 438 , 10171021 (2005)

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However, studies to evaluate the regenerative potential of AT-MSCs-derived EVs in other tissues suggest that they may not fully replicate the regenerative efficacy of living AT-MSCs (147, 148)