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[DOI] [PubMed] [Google Scholar] 31.Franca EL, et al

2001 Oct;11(10):899-907

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In vitro experiments demonstrated that agrin treatment significantly downregulated PDGFR and claudin-5 expression in a blood-brain barrier co-culture model comprising human brain microvascular endothelial cells and pericytes, suggesting that agrin may induce pericyte death and impair the integrity of the blood-brain barrier

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