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Skin Cleansing: The injection area, typically the arm, is cleaned and sterilized to prevent infections

Clinically, neuropathy is divided into: Large-fiber neuropathy: Impairs proprioception, vibration sense, deep tendon reflexes

Cagrilintide and tirzepatide are discussed together because both are once-weekly injectables that reduce appetite and bodyweight, and both slow gastric emptying as part of that effect

the lactate dyscrasia theory) proposes that mitochondrial dysfunction partly contributes to an accumulation of lactate in the junction of motor neurons and muscle cells (the neuromuscular junction (NMJ)) leading to death of both the nerve and muscle cells, thereby requiring the remaining muscle cells to work harder-than-normal to generate the force necessary for motor control

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