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ROS causes GSTs-JNK-c-Jun complex formation blocking JNK signaling pathway and preventing the events associated with this signaling cascade

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Thus, activated ERK1/2 plays an important regulatory role in physiological and pathological processes at the gene level (199)

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Toft G, Thulstrup AM, Jonsson BA, Pedersen HS, Ludwicki JK, Zvezday V, Bonde JP: Fetal loss and maternal serum levels of 2,2',4,4',5,5'-hexachlorbiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p, p'-DDE) exposure: a cohort study in Greenland and two European populations