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On the one hand, ERS serves as an inducer of autophagy

The discrepancies in the biotoxicity of ferroptosis-inducers in animal models and humans contribute to erroneous assessments of the safety and efficacy of therapies

Vascular superoxide is primarily derived from nicotinamide adenine dineucleotide phosphate (NADPH) oxidase when stimulated by hormones, such as angiotensin II (AT-II), endothelin-1 (ET-1) and urotensin II

Li Y, He X, Sun B, Hu N, Li J, You R et al (2024) Combined exposure of beta-cypermethrin and emamectin benzoate interferes with the HPO axis through oxidative stress, causing an imbalance of hormone homeostasis in female rats

PMID: 41843713 Folia Histochem Cytobiol Ginsenoside Rg3 inhibits Ang II-induced cardiac fibrosis via the GLP-1 receptor signaling pathway