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10.1021/tx400431k Chem

Nearly 30 systematic reviews and meta-analyses have been published regarding ALAs beneficial effects in managing diabetes and its complications (Table 4)

In general, KRAS comutations affect the immune regulation of the KRAS-driven TME by recruiting immunosuppressive cells and increasing PD-L1 expression

Collectively, these studies highlight that pharmacological activation of Nrf2 can reduce ferroptosis and improve neurological deficits in preclinical models of ICH