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Nonlinear regression of the STAND-protein binding data was performed using the HillLangmuir equation: B = B max [STAND protein]/[ K d + [STAND protein]] where B is the concentration of the STAND protein bound to the antigen, B max is the number of total binding sites, [STAND protein] is the free STAND concentration, and K d is the dissociation constant

No existing study has been found to report the interactions between MH and 1

Evidence shows that p53 downregulates SLC7A11 expression, blocking cystine uptake, impairing GPX4 activity, and promoting the intracellular accumulation of LPO, ultimately triggering ferroptosis

Researchers using degraded peptide will see inconsistent results, wasted experimental resources, and confounded data that cannot be interpreted reliably

These two cycles also link with the trans-sulfuration pathway, which plays a critical role in the regulation of the redox state by producing glutathione (3)