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10.1038/s41598-020-57758-5 63 GuoJ

Perilipin 2 (PLIN2) is a ubiquitously expressed protein that plays an important role in the pathophysiology of MASH and contributes to disease progression

doi: 10.1080/1745039X.2020.1726719

Furthermore, the threshold effect is consistent with the concept that methionine synthase activity may become saturated beyond a certain B12 concentration [17], explaining the diminishing returns observed at higher levels