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We crossed Atp7b / mice with Prnp / mice and analyzed the degree of liver damage in the resulting double knockout strain (Atp7b / :Prnp / )

Abstract Background The tripeptide glutathione (L-gamma-glutamyl-cysteinyl-glycine) is essential to cell survival, and deficiency in cardiac and systemic glutathione relates to heart failure progression and cardiac remodelling in animal models