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In CAP, oxidative stress is caused by an imbalance in the generation of reactive oxygen species (ROS) and the body's ability to detoxify or repair the associated damage [15]

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Indeed, ROS aggregation may activate c-Jun amino-terminal kinase (JNK) signaling and block the PPAR-FGF21 axis, thereby impeding mitochondrial -oxidation and ketogenesis [119]

[1] [4] Healthcare providers should consider alternative therapies with established safety profiles in pregnant or lactating patients whenever possible, and if glutathione injection is deemed necessary, close monitoring of both mother and child is recommended throughout treatment

Pediatric Glutathione injection should be used with caution in neonates, premature infants, and children, especially when it is administered by intramuscular injection