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In ovarian cancer, tumor-released mesothelin, which is linked to a glycosylphosphatidylinositol (GPI) anchor, binds to MR on macrophages, driving their polarization toward the TAM phenotype, which supports tumor growth and suppresses the immune response

Short-term effects of metformin and myo-inositol in women with polycystic ovarian syndrome (PCOS): a meta-analysis of randomized clinical trials

Fu, M., Zhang, W., Wu, L., Yang, G., Li, H

In addition to commonly used iron chelating therapy, regulating hepcidin levels may also help alleviate iron overload in -thalassemia patients, due to their typically low hepcidin levels