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18,2627 In mammals, including humans, protein restriction (PR) diets without malnutrition also show beneficial effects: PR contributes to reduced mortality and incidence of age-associated diseases, ultimately supporting longevity

(5) Reduces the levels of excitatory neurotransmitters and increases the transmission of inhibitory neurotransmitters by inhibiting carbonic anhydrase (CA), especially CA II and CA IV (White, 2005)

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Delays in treatment are associated with a dramatic increase in the rate of hepatotoxicity for both routes

Blood (2009) 113:121324