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By using propidium iodide (PI), a membrane-impermeable DNA-binding dye, we observed no notable increase in PI uptake under all tested conditions (Supplementary Fig

Diet plays a role

Figure 2 Excessive intracellular Ca 2+ levels trigger the opening of the mitochondrial permeability transition pore (MPTP), resulting in the loss of mitochondrial membrane potential and hindering ATP production (50)