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The Azo-tagged Azurin was reverted to the trans -state by exposure to 430 nm light and then mixed with the SAC-purified mScarlet protein lacking the Azo-tag

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Out of the various selected targets human endothelial MMP3, nitric oxide synthase, and DJ-1 showed a good binding score with SC, shown in Table 2

studies have confirmed the upregulation of HIF-1 and its target genes, such as pyruvate dehydrogenase kinase 1 (PDK1) and lactate dehydrogenase A (LDHA), specifically within the CD68+ macrophages infiltrating the kidneys of LN patients and lupus-prone mice ( Complex positive feedback loops exist between glycolysis and innate immune signaling pathways, exacerbating the inflammatory storm in LN

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