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it is intricately interlinked with other core pathological processes in AD, including neuroinflammation and mitochondrial dysfunction

However, two arguments support a different GSH binding mode in MGST1: 1) in electron crystallography maps of MPGES1 the horseshoe shape of GSH could be observed at a similar resolution 26 , and 2) MGST1 has the unique ability to use N-acetyl-L-cysteine as substrate supporting a different GSH site (discussed further below)

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Vitamin B complex , a group of eight essential vitamins, plays a crucial role in maintaining overall health, including the health of mitochondria

IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation. Arteriosclerosis, Thrombosis, and Vascular Biology, vol