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Using a luciferase reporter assay, the authors confirmed that miR-181a, miR-135a and miR-302c targeted directly PLAG1 which is an IGF2 transcription factor (102)

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People began calling their results "remarkable" and "life-changing." Over time, LifeWave conducted multiple clinical studies on X39, including double-blind trials measuring things like copper peptide levels in the blood, brain coherence via EEG scans, and improvements in sleep and recovery markers