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Linear Angiotensin IV Analogues and Incorporation of Unnatural Amino Acids After systematic structure activity studies (SAR) of Ang IV analogues, involving glycine and D-amino acid scans in combination with displacement and incorporation of various alternative amino acid residues it became clear that the N-terminal Val-Tyr-Ile residues of the peptide ligands were important for high affinity to the specific binding site identified (Sardinia et al., 1993), named the AT4 receptor (de Gasparo et al., 1995)

Stock No.032411) mice were obtained from the Jackson Laboratory (Bar Harbor, ME, USA)

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A 40 oligomers identified as a potential biomarker for the diagnosis of Alzheimers disease

LDM_res v1.0 GitHub release is archived on Zenodo (Franch et al., 2024) and allows for downloading the code to reproduce the presented experiments ( All authors conceived and conceptualized the study