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Identification of potential biomarkers in the peripheral blood mononuclear cells of relapsing-remitting multiple sclerosis patients

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Increased sensitivity to a drug is usually signaled by exaggerated responses to small or moderate doses

Monitoring response to treatment involves: Clinical assessment of symptom improvement, including mouth ulcer frequency FBC to confirm resolution of anaemia and reticulocyte response Ongoing monitoring of neurological symptoms if present Routine repeat measurement of serum B12 levels shortly after starting injections is not generally recommended as results may be misleadingly high