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10.1111/bph.13847 26 IsraelY.KarahanianE.EzquerF.MoralesP.EzquerM.Rivera-MezaM.et al

We speculate that GlyNAC represents three forces which could be operating simultaneously to result in such widespread improvements: (1) Correction of GSH deficiency, which results in correction of OxS and mitochondrial dysfunction

Inflammation is primarily triggered by the NF-B signaling pathway, which regulates proinflammatory genes such as ALOX5 and PTGS2, responsible for encoding enzymes like 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2)