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A prior model used to fit the U597C data (Smith et al., 2023), suggested that this disulfide reduction occurs on a similar time frame as flavin reduction and is therefore estimated to also have a rate constant on the 1000 s s 1 timescale

(1997) Forced swim test-induced neurochemical, endocrine and immune changes in the rat Pharmacol

However, it provides an additional rotation option for individuals who need to rotate among three anatomical regions to prevent site irritation during long-term therapy

Nikolova VL, Hall MRB, Hall LJ, Cleare AJ, Stone JM, Young AH

siRNAs used in this study were as follows: Gpx4 (1 nM, s131172, Thermo Fisher Scientific), Ripk3 (10 nM, s140858, Thermo Fisher Scientific), Abcb8 (1 nM, s168896, Thermo Fisher Scientific), and Top2b (10 nM, s166822, Thermo Fisher Scientific)