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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Todd D et al

Lenormand, T., Bourguet, D., Guillemaud, T

A comprehensive file of all comments received on drafts of each EHC monograph is maintained and is available on request

Glycine is synthesized primarily through the enzymatic conversion of serine-by-serine hydroxymethyltransferase (SHMT), which operates in both the cytosol and mitochondria, catalyzing the reversible transfer of a hydroxymethyl group from serine to tetrahydrofolate (THF), producing glycine and 5,10-methylene-THF