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Both are in early development

As summarized by Stier, Vos, and Kenley in 2013, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, while the compound's tolerability profile remained comparable to placebo

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Our study enhances these findings by integrating advanced control methods, such as Pontryagins minimum principle and Riccati equations, to dynamically regulate macrophage activity and prevent fibrosis progression with greater precision

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