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Erastin sensitizes glioblastoma cells to Temozolomide by restraining xCT and cystathionine--lyase function

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations E-GPx: extracellular glutathione peroxidase C-GPx: cellular glutathione peroxidase GPx-GI: gastrointestinal glutathione peroxidase GPx: seleniumdependent glutathione peroxidase IBD: inflammatory bowel disease DSS: dextran sodium sulfate GI: gastrointestinal t-BuOOH: tert-butyl hydroperoxide GSH: glutathione SSC: saline-sodium citrate GAPD: glyceraldehyde-3 phosphate dehydrogenase References Parks DA, Bulkley GB, Granger DN 1983 Role of oxygen-derived free radicals in digestive tract diseases

The collaborative effort between Birsoys metabolic regulation group and Richard Hites structural biology lab was instrumental in resolving the biochemical features of the SLC33A1 transporter

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Measurement of encapsulated Mg 2+ concentration The internal Mg 2+ concentration of the vesicles was measured using mag-fura-2 according to the procedures described earlier 39