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PubMed Rena G, Hardie DG, Pearson ER

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However, issues with graft survivability, disease transmission, and integration have motivated tissue engineers to develop newer composite scaffolds that guide localized regeneration of the cartilage and bone layers of an osteochondral unit

Originally developed for Parkinsons and Alzheimers disease research, Tesofensines significant effects on body weight were discovered during clinical trials redirecting research interest toward its metabolic potential

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