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A burning or sharp pain during injection (this may indicate you've hit a blood vessel or muscle) Medication leaking out of the injection site Injection site reactions like bruising, swelling or redness that worsen after the injection Shortness of breath call 911 if this occurs The medication isn't having its intended effects, such as reduced appetite

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Only 30% received DOR as part of a three-drug regimen with two nucleoside reverse transcriptase inhibitor (NRTI), of whom 92% received the fixed dose combination and 8% received the single agent

& Chaykin, S