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.,XiaoM,ZhongH,XiaL,TaoYYinHPathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria.2017;111:316327

It may also contribute to subtle detrimental effects on cognitive function 38 and may have a wide array of other psychiatric manifestations, such as propensity to gamble

Glycogen synthase kinase-3 mediated regulation of matrix metalloproteinase-9 and its involvement in oral squamous cell carcinoma progression and invasion

To date, three key experimental strategies are used to manipulate or remove senescent cells: depleting senescent cells, manipulating triggering pathways of senescence (mainly P16 INK4A and P21 CIP1 ), and targeting senescent cells and/or their secreted factors pharmacologically [7]

In animal models, acupuncture has an antioxidant effect by elevating the activity of enzymes such as SOD, GSH peroxidase, and CAT, and suppressing pro-oxidant markers including malondialdehyde and ROS [179, 180]