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Comment: One commenter, while generally supporting the proposal and the first alternative, expressed concern that in biosimilar markets with few participants, the proposal and first alternative would provide manufacturers a perverse incentive to employ aggressive rebate strategies or otherwise manipulate pricing data in order that competitor products' ASP data be used as the basis for a more favorable payment limit

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Thus, there is a highly unmet medical need to ameliorate hyperphagia and obesity related to POMC-MC4R pathway deficiency

Both BAL fluid GSSG and GSH:GSSG were (differentially) correlated with FEV 1 (Table 2 and Figure 5A)

Immunization with heat-killed Mycobacterium bovis bacille CalmetteGuerin (BCG) in Eurocine L3 adjuvant protects against tuberculosis