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In turn, this may contribute to the development of depression by increasing oxidative stress, DNA damage, and cell death in the body ( A 2020 study with 132 children and teens, 89 with and 43 without depression, found that the participants with depression had lower B12 levels and higher levels of homocysteine compared with those without depression ( In addition to depressive symptoms, low or deficient B12 levels may lead to other mental conditions, including psychosis and mood disorders ( Because a deficiency in B12 negatively impacts the central nervous system, people with low or deficient B12 levels may feel foggy-headed and have difficulty concentrating and completing tasks ( Fortunately, studies show that mental impairment related to low B12 levels can improve with B12 treatment

No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

For pernicious anaemia or malabsorption disorders , the standard treatment in the UK involves intramuscular (IM) injections of hydroxocobalamin, the preferred form of B12

If you are found to have a Vitamin B12 deficiency diagnosed through blood tests, or if you have medical conditions that impede your bodys ability to absorb Vitamin B12, such as pernicious anemia, celiac disease, or Crohns disease, you could potentially qualify for these injections

The Institute of Medicine reports that no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy individuals. However, if youre not deficient in vitamin B12 to begin with or you dont address the underlying reasons you might be deficient, i.e