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Receptor-mediated targeting extends beyond platelets

R.ZhangX.et al (2024)

doi: 10.1158/0008-5472.CAN-18-3527 105 LiYWuSZhaoYDinhTJiangDSelfridgeJEet al

Nevertheless, no further investigation was performed with regard to clinical efficacy due to safety concerns

By producing inflammatory mediators that are lethal to tumor cells, such as TNF-Alfa, MIP-1 ALFA, H2O2, and NO, chemokines like CXCL8, CXCL1, CXCL2, and CXCL3 attract it to the tumor microenvironment [55]