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(PubMed) Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PW, Kiel DP

Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant glioma following local administration

Moreover, previous efforts to characterize archival pathological tissues have provided new insights into the tumour microenvironment using IMC in breast cancer 49,50 and melanoma 51 as well as in post-mortem COVID-19 specimens using IBEX 52

In addition, the benchmarking approach provides an alternative to the traditional validation of NAMS against apical effects in rodent studies but rather tries to evaluate the NAMs in the context of making protective safety decisions ( in vitro culture methodologies (van der Zalm et al., 2022)