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However, the diameter ranges with differences in the frequency of pain are not clear, since painful insertions decreasing from 63% to 31% in the 2332 G range have been reported [16] whereas other authors found no differences in injection pain when comparing needles in narrower ranges, such as 2630 G [17, 18]

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A WHO consultation identified the most vulnerable groups as elderly individuals, infants, preschool-aged children, and pregnant or lactating women, due to either increased nutritional demands or impaired absorption capacity ( Addressing the prevention of B12 deficiency and its public health implications requires a comprehensive, life-course approach based on integrated strategies targeting early detection, dietary optimisation, and effective supplementation, in order to mitigate the long-term consequences of inadequate cobalamin status ( Intramuscular (IM) injection is the most invasive and costly administration method, requiring trained personnel and clinical visits